RP1: Next Generation Sequencing platform to detect variants underlying hereditary intrahepatic cholestasis
Detektion genetischer Varianten bei hereditärer intrahepatischer Cholestase mittels NGS Technologie
RP2a: In silico prediction of consequences of cholestasis- associated variants
In silico Modellierung Cholestase-assoziierter Varianten
RP2b: In vitro analysis of consequences of cholestasis-associated variants
In vitro Analyse Cholestase-assoziierter Varianten
RP3: Patient iPSC-based hepatic organoid models and CRISPR/Cas engineered controls
iPSC Modelle, CRISPR/Cas Organoide
RP5: Gut microbiota changes in familial intrahepatic cholestasis – diagnostic and pathophysiological implications
Darm Mikrobiom Veränderungen in hereditären Cholestasen
